What is the ideal depth to microneedle for hair regrowth? Journal time!

Posted on December 3, 2025

microneedling for hair regrowth

Microneedling is great for skin quality and for hair regrowth. For skin it will help improve collagen, elastin, skin quality, pore size, and more. For hair microneedling has been shown to stimulate hair growth, statistically significantly, on its own- without products, just the needling.

The theory on why microneedling works in a medical setting with high grade sterile needles placed to a correct depth (Yes, this is me pleading for you to not try this at home), is that it stimulates the wound healing cascade, which causes the release of growth factors, hair follicle stem cells, and new vascularization of the scalp.

Scalp anatomy

How deep should you go? If you look at the scalp, you will see a wide range of “thickness” of the scalp. In my quest to understand this as much as I can, I found an original paper about scalp anatomy. For this I went totally old school, and found a paper published in 1972,The Thickness of Human Scalp: Normal and Bald” from the Journal of Investigative Dermatology. They studied the thickness of the layers in normal and bald scalps. This was done on male and female cadavers and on living male subjects at different stations of hair loss.

A plastic surgical textbook estimated the layer thicknesses: Epidermis 1.5mm, Dermis 2-4mm, Subcutaneous layer 4-7 mm (though some have 20mm thickness), and Galea (thin). It is thinner near the crown of the head, and thicker near the back of the head.

The hair follicle and hair bulb, where growth occurs, is in the dermis. This is where the blood supply, nerves, and oil glands are. The base of the hair follicle may extend into the subcutaneous layer below the dermis, where blood supply is necessary to nourish the growing hair.

Journal article: ideal depth for microneedling for hair regrowth

In this study they wanted to look at how deep should you microneedle? They looked at 60 patients, ages 18-45 who were showing signs of androgenetic alopecia (AGA). They had 3 groups.  “Microneedling in androgenetic alopecia; comparing two different depths of microneedles”, Cosmetic Dermatology

Study:

What we do at Lauren Greenberg MD

This is still a rapidly evolving landscape. I put these two studies in here to show that microneedling is CLEARLY a good thing to combat hair thinning and hair loss. Every study supports it, and shows statistically larger improvements when done in combination therapy. That science is clear.

What is not clear yet are the other parameters. How deep, how often, for how long. This study at 0.6mm vs 1.2mm was done biweekly. There are other studies which show that may be “too frequent” if doing a deeper depth as it does not give the scalp time to recover. There are some studies which indicate if you go deeper that it would allow fewer treatments. When looking at the anatomy, it seems the dermis is where the action is. The lower depth needles would not be reaching that. So is the key to go slightly deeper, less frequently?

The scalp study above also indicates that scalp thickness varies a lot, by gender, age, and site on the scalp. We feel that you want to aim for the dermis/subcutaneous junction. That is where the hair follicle and its blood supply live. Just as with our microneedling treatments to the face, we make an individual diagram of each patient’s anatomy. During the first treatment we use the feedback we get and adjust the depth to aim for that junction. So we think the answer is going to be much more individual- Man/woman, Age, Where on Scalp.

Medical references

Microneedling in androgenetic alopecia; comparing two different depths of microneedles, Cosmetic Dermatology

The Thickness of Human Scalp: Normal and Bald” from the Journal of Investigative Dermatology. 

The Scalp


The information provided on this website is for general informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider for any questions regarding your health or medical condition.

This blog has been authored by Dr. Lauren Greenberg

Dr. Lauren Greenberg is a Stanford-trained, board-certified plastic surgeon who brings over two decades of experience and a strong commitment to natural-looking results. She is known for combining advanced techniques with an honest, thoughtful approach to help patients feel confident and empowered.

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