Microneedling for scars- old and new- a journal analysis

Posted on December 12, 2025

What does microneedling do?

Microneedling uses tiny needles to stimulate the skin to rejuvenate it- tighten it, help with stretch marks, scar remodeling, and hair growth. Its fancier medical name is “percutaneous collagen induction therapy.” It is exciting because it is thought to not have post inflammatory hyperpigmentation, so it is used in darker skin phototypes (Fitzpatrick IV through VI seen in Asia and the Middle East).

How is it thought to help with scars

Microneedling helps in many ways. Studies in animal and human models show:

Journal article on microneedling of scars- synopsis

This was a study out of dermatology.

Findings?

Both microneedling and microneedling with radiofrequency improved scar appearance from baseline without serious events. They concluded that studies are needed to develop standardized treatment protocols.

When you look at the study, you see they all vary in needle depth, when they start doing microneedling, spacing of treatments, what topical products they put on with the microneedling treatment, and how many treatments they do. Where did they agree?

There is very a small risk of issues, which are reported as hyperpigmentation, scabbing, bruise, railroad tracks, acne flare, and herpes reactivation.

What did they conclude from this study? They evaluated scars by the patient and the investigator. They used scar scales to stratify.

  • Combination therapy was more effective at scar improvement than microneedling or RF microneedling alone. (Studies used laser, PRP, glycolic acid peel, TCA peel, and topical amniotic stem cells.)
  • 50-100% patient satisfied. 1/3 would want further treatment
  • 94% would recommend to others.

They conclude that microneedling is well tolerated and gives clinical improvement in scarring. They found patients tolerated it better than laser treatment of scars.

Dr. Greenberg’s thoughts on microneedling scars

I am a fan of microneedling. I see great changes in skin and hair improvement. We have been doing the microneedling with topical Age Zero exosomes, and like our results.

As for scar treatment, I want to know more. I have blogged before about microneedling of scars, and the real question for me is when? how often? what is the spacing? what depth should you aim for?

Though this meta study did not show issues with pigmentation, I always worry about pigmentation in my darker skinned patients. Any inflammation can lead to pigment.

So we offer it, but I cannot fully run with this yet- I need to see better definition of protocols.

Medical Citation

Microneedling for the Treatment of Scars: An Update for Clinicians – PMC (nih.gov), Clinic of Cosmetic Investigative Dermatology, December 2020.

 


The information provided on this website is for general informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider for any questions regarding your health or medical condition.

This blog has been authored by Dr. Lauren Greenberg

Dr. Lauren Greenberg is a Stanford-trained, board-certified plastic surgeon who brings over two decades of experience and a strong commitment to natural-looking results. She is known for combining advanced techniques with an honest, thoughtful approach to help patients feel confident and empowered.

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